E37G (p.Glu37Gly) variant of KEAP1 (Q14145)
E37G (p.Glu37Gly) in KEAP1 (Q14145) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
E37G (p.Glu37Gly) variant details
- p.Glu37Gly
- TOPMed rs1465714155
- gnomAD rs1465714155
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.26
- CADD 23.30
- PolyPhen-2 0.43
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available