D29E (p.Asp29Glu) variant of KEAP1 (Q14145)
D29E (p.Asp29Glu) in KEAP1 (Q14145) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
D29E (p.Asp29Glu) variant details
- p.Asp29Glu
- ExAC rs746477922
- TOPMed rs746477922
- gnomAD rs746477922
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.06
- CADD 17.30
- PolyPhen-2 0.00
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available