C23G (p.Cys23Gly) variant of KEAP1 (Q14145)
C23G (p.Cys23Gly) in KEAP1 (Q14145) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
C23G (p.Cys23Gly) variant details
- p.Cys23Gly
- Ensembl rs2144630989
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.04
- CADD 10.70
- PolyPhen-2 0.01
- SIFT 0.68
- Most common in the Non-Finnish European population (allele frequency 7.3e-06)
- Structural context available