P61R (p.Pro61Arg) variant of KDM6B (Lysine-specific demethylase 6B)
P61R (p.Pro61Arg) in KDM6B (Lysine-specific demethylase 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
P61R (p.Pro61Arg) variant details
- p.Pro61Arg
- gnomAD rs1472409768
- Missense
- Variant Prioritization Score for Impact Estimate 0.381
- REVEL 0.23
- MetaLR 0.10
- MetaSVM -0.94
- CADD 24.30
- PolyPhen-2 0.71
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available