P35H (p.Pro35His) variant of KDM6B (Lysine-specific demethylase 6B)
P35H (p.Pro35His) in KDM6B (Lysine-specific demethylase 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
P35H (p.Pro35His) variant details
- p.Pro35His
- TOPMed rs1483985578
- gnomAD rs1483985578
- Missense
- Variant Prioritization Score for Impact Estimate 0.423
- REVEL 0.24
- MetaLR 0.14
- MetaSVM -0.81
- CADD 25.40
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available