H64R (p.His64Arg) variant of KDM6B (Lysine-specific demethylase 6B)
H64R (p.His64Arg) in KDM6B (Lysine-specific demethylase 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
H64R (p.His64Arg) variant details
- p.His64Arg
- cosmic curated COSV10503
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.16
- MetaLR 0.10
- MetaSVM -1.00
- CADD 24.40
- PolyPhen-2 0.61
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available