H34Y (p.His34Tyr) variant of KDM6B (Lysine-specific demethylase 6B)
H34Y (p.His34Tyr) in KDM6B (Lysine-specific demethylase 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
H34Y (p.His34Tyr) variant details
- p.His34Tyr
- ESP rs377441486
- ExAC rs377441486
- TOPMed rs377441486
- gnomAD rs377441486
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.11
- MetaLR 0.05
- MetaSVM -1.01
- CADD 23.30
- PolyPhen-2 0.10
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 0.00019)
- Structural context available