G26R (p.Gly26Arg) variant of KDM6B (Lysine-specific demethylase 6B)
G26R (p.Gly26Arg) in KDM6B (Lysine-specific demethylase 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
G26R (p.Gly26Arg) variant details
- p.Gly26Arg
- gnomAD rs1400214515
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.19
- MetaLR 0.10
- MetaSVM -0.82
- CADD 28.90
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available