C24Y (p.Cys24Tyr) variant of KDM6B (Lysine-specific demethylase 6B)
C24Y (p.Cys24Tyr) in KDM6B (Lysine-specific demethylase 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
C24Y (p.Cys24Tyr) variant details
- p.Cys24Tyr
- gnomAD rs1302314690
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.18
- MetaLR 0.08
- MetaSVM -0.93
- CADD 26.30
- PolyPhen-2 0.55
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available