A4A (p.Ala4Ala) variant of KDM6B (Lysine-specific demethylase 6B)

Name: KDM6B A4A (p.Ala4Ala) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-20
License: https://catvariant.com/terms-of-use

A4A (p.Ala4Ala) in KDM6B (Lysine-specific demethylase 6B) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.

A4A (p.Ala4Ala) variant details

p.Ala4Ala
gnomAD 17-7845566-A-G
Synonymous
Variant Prioritization Score for Impact Estimate 0.538
CADD 14.80
Most common in the Non-Finnish European population (allele frequency 1.8e-06)
Structural context available
Literature evidence available