G19G (p.Gly19Gly) variant of KCNT1 (Q5JUK3)
G19G (p.Gly19Gly) in KCNT1 (Q5JUK3) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
G19G (p.Gly19Gly) variant details
- p.Gly19Gly
- gnomAD 9-135702315-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.292
- AlphaMissense 0.16
- MetaLR 0.28
- MetaSVM -0.76
- CADD 6.87
- PolyPhen-2 0.84
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available