R74G (p.Arg74Gly) variant of KCNQ3 (O43525)
R74G (p.Arg74Gly) in KCNQ3 (O43525) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
R74G (p.Arg74Gly) variant details
- p.Arg74Gly
- ExAC rs776548429
- gnomAD rs776548429
- Missense
- Variant Prioritization Score for Impact Estimate 0.55
- REVEL 0.45
- CADD 23.40
- PolyPhen-2 0.03
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 4.2e-05)
- Structural context available