F527L (p.Phe527Leu) variant of KCNQ2 (O43526)

F527L (p.Phe527Leu) in KCNQ2 (O43526) is a missense change. Clinical records from ClinVar and UniProt describe it as pathogenic in the context of Early-infantile DEE; Seizures, benign familial neonatal, 1. The record also includes structural context.

F527L (p.Phe527Leu) variant details