W15G (p.Trp15Gly) variant of KCNQ1 (Potassium voltage-gated channel subfamily KQT member 1)
W15G (p.Trp15Gly) in KCNQ1 (Potassium voltage-gated channel subfamily KQT member 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
W15G (p.Trp15Gly) variant details
- p.Trp15Gly
- gnomAD 11-2445141-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.459
- REVEL 0.42
- ESM-1b 0.00
- AlphaMissense 0.06
- MetaLR 0.84
- MetaSVM 0.28
- CADD 18.10
- Most common in the HGDP:SARDINIAN population (allele frequency 0.056)
- Structural context available
- Literature evidence available