T64K (p.Thr64Lys) variant of KCNJ3 (P48549)
T64K (p.Thr64Lys) in KCNJ3 (P48549) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
T64K (p.Thr64Lys) variant details
- p.Thr64Lys
- ExAC rs758323912
- gnomAD rs758323912
- Missense
- Variant Prioritization Score for Impact Estimate 0.575
- REVEL 0.55
- CADD 18.50
- PolyPhen-2 0.01
- SIFT 0.87
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available