F8S (p.Phe8Ser) variant of KCNJ3 (P48549)
F8S (p.Phe8Ser) in KCNJ3 (P48549) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
F8S (p.Phe8Ser) variant details
- p.Phe8Ser
- ESP rs376120670
- ExAC rs376120670
- TOPMed rs376120670
- gnomAD rs376120670
- Missense
- Variant Prioritization Score for Impact Estimate 0.524
- REVEL 0.46
- CADD 24.00
- PolyPhen-2 0.33
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available