F85S (p.Phe85Ser) variant of KCNJ3 (P48549)
F85S (p.Phe85Ser) in KCNJ3 (P48549) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data, published literature, and structural context.
F85S (p.Phe85Ser) variant details
- p.Phe85Ser
- gnomAD 2-154699029-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.678
- REVEL 0.71
- CADD 26.20
- PolyPhen-2 0.39
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available