S35G (p.Ser35Gly) variant of KCNJ2 (P63252)
S35G (p.Ser35Gly) in KCNJ2 (P63252) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
S35G (p.Ser35Gly) variant details
- p.Ser35Gly
- gnomAD rs1192608882
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.25
- MetaLR 0.39
- MetaSVM -0.50
- CADD 20.60
- PolyPhen-2 0.00
- SIFT 0.82
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available