F15S (p.Phe15Ser) variant of KCNE2 (Q9Y6J6)
F15S (p.Phe15Ser) in KCNE2 (Q9Y6J6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
F15S (p.Phe15Ser) variant details
- p.Phe15Ser
- ESP rs374431902
- ExAC rs374431902
- TOPMed rs374431902
- gnomAD rs374431902
- Missense
- Variant Prioritization Score for Impact Estimate 0.65
- REVEL 0.72
- ESM-1b 0.00
- AlphaMissense 0.73
- MetaLR 0.79
- MetaSVM 0.75
- CADD 24.90
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available