T10T (p.Thr10Thr) variant of KCNE1 (P15382)

Name: KCNE1 T10T (p.Thr10Thr) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-10-09
License: https://catvariant.com/terms-of-use

T10T (p.Thr10Thr) in KCNE1 (P15382) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.

T10T (p.Thr10Thr) variant details

p.Thr10Thr
rs187686559
gnomAD 21-34449605-C-A
Synonymous
Variant Prioritization Score for Impact Estimate 0.0884
CADD 1.10
Population evidence available
Structural context available
Functional MAVE scores for KCNE1: score 1.42
Cited in: A systematic approach to assessing the clinical significance of genetic variants. (PMID 24033266)
Cited in: Genetic polymorphisms in KCNQ1, HERG, KCNE1 and KCNE2 genes in the Chinese, Malay and Indian populations of Singapore. (PMID 16487223)