R25H (p.Arg25His) variant of KCNB1 (Q14721)
R25H (p.Arg25His) in KCNB1 (Q14721) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
R25H (p.Arg25His) variant details
- p.Arg25His
- cosmic curated COSV10530
- Missense
- Variant Prioritization Score for Impact Estimate 0.713
- REVEL 0.65
- CADD 29.10
- PolyPhen-2 0.98
- SIFT 0.00
- Population evidence available
- Structural context available