R26P (p.Arg26Pro) variant of KCNA1 (Q09470)
R26P (p.Arg26Pro) in KCNA1 (Q09470) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
R26P (p.Arg26Pro) variant details
- p.Arg26Pro
- gnomAD 12-4911455-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.27
- MetaLR 0.66
- MetaSVM -0.21
- CADD 22.30
- PolyPhen-2 0.00
- SIFT 0.29
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available