P25T (p.Pro25Thr) variant of KCNA1 (Q09470)
P25T (p.Pro25Thr) in KCNA1 (Q09470) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
P25T (p.Pro25Thr) variant details
- p.Pro25Thr
- gnomAD 12-4911451-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.485
- REVEL 0.27
- MetaLR 0.75
- MetaSVM 0.28
- CADD 20.70
- PolyPhen-2 0.04
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- Literature evidence available