G22D (p.Gly22Asp) variant of KCNA1 (Q09470)
G22D (p.Gly22Asp) in KCNA1 (Q09470) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
G22D (p.Gly22Asp) variant details
- p.Gly22Asp
- gnomAD rs1237801961
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.23
- CADD 21.80
- PolyPhen-2 0.02
- SIFT 0.29
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available