D32N (p.Asp32Asn) variant of KCNA1 (Q09470)
D32N (p.Asp32Asn) in KCNA1 (Q09470) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
D32N (p.Asp32Asn) variant details
- p.Asp32Asn
- NCI-TCGA Cosmic COSV1012
- NCI-TCGA Cosmic COSV6683
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.532
- REVEL 0.39
- CADD 23.20
- PolyPhen-2 0.01
- SIFT 0.20
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available