D31G (p.Asp31Gly) variant of KCNA1 (Q09470)
D31G (p.Asp31Gly) in KCNA1 (Q09470) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
D31G (p.Asp31Gly) variant details
- p.Asp31Gly
- NCI-TCGA Cosmic COSV1012
- NCI-TCGA Cosmic COSV6683
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.25
- CADD 22.20
- PolyPhen-2 0.00
- SIFT 0.60
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available