P74S (p.Pro74Ser) variant of JMJD4 (Q9H9V9)
P74S (p.Pro74Ser) in JMJD4 (Q9H9V9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
P74S (p.Pro74Ser) variant details
- p.Pro74Ser
- gnomAD rs1171589258
- Missense
- Variant Prioritization Score for Impact Estimate 0.205
- REVEL 0.03
- ESM-1b 0.58
- AlphaMissense 0.08
- MetaLR 0.01
- MetaSVM -0.92
- CADD 11.17
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available