Y44C (p.Tyr44Cys) variant of JAK2 (Tyrosine-protein kinase JAK2)
Y44C (p.Tyr44Cys) in JAK2 (Tyrosine-protein kinase JAK2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The record also includes variant effect predictions and structural context.
Y44C (p.Tyr44Cys) variant details
- p.Tyr44Cys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- MetaLR 0.69
- MetaSVM 0.48
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available