E12K (p.Glu12Lys) variant of JAK2 (Tyrosine-protein kinase JAK2)
E12K (p.Glu12Lys) in JAK2 (Tyrosine-protein kinase JAK2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The record also includes variant effect predictions and structural context.
E12K (p.Glu12Lys) variant details
- p.Glu12Lys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- MetaLR 0.33
- MetaSVM -0.43
- SIFT 0.06
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available