D24G (p.Asp24Gly) variant of JAK2 (Tyrosine-protein kinase JAK2)
D24G (p.Asp24Gly) in JAK2 (Tyrosine-protein kinase JAK2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
D24G (p.Asp24Gly) variant details
- p.Asp24Gly
- gnomAD 9-5022058-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.19
- AlphaMissense 0.10
- MetaLR 0.33
- MetaSVM -0.63
- CADD 22.70
- PolyPhen-2 0.00
- Population evidence available
- Structural context available
- Literature evidence available