W218* (p.Trp218Ter) variant of ITPR2 (Q14571)
W218* (p.Trp218Ter) in ITPR2 (Q14571) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.87 / 1. The record also includes population frequency data and structural context.
W218* (p.Trp218Ter) variant details
- p.Trp218Ter
- NCI-TCGA Cosmic COSV1011
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.872
- CADD 39.00
- UniProt: Variant assessed as somatic; high impact.
- Population evidence available
- Structural context available