H164Y (p.His164Tyr) variant of ITPR2 (Q14571)
H164Y (p.His164Tyr) in ITPR2 (Q14571) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
H164Y (p.His164Tyr) variant details
- p.His164Tyr
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.63
- REVEL 0.56
- CADD 23.10
- PolyPhen-2 0.12
- SIFT 0.06
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available