F161L (p.Phe161Leu) variant of ITPR2 (Q14571)
F161L (p.Phe161Leu) in ITPR2 (Q14571) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
F161L (p.Phe161Leu) variant details
- p.Phe161Leu
- TOPMed rs1042977981
- gnomAD rs1042977981
- Missense
- Variant Prioritization Score for Impact Estimate 0.572
- REVEL 0.67
- CADD 18.20
- PolyPhen-2 0.01
- SIFT 0.31
- Population evidence available
- Structural context available