D232G (p.Asp232Gly) variant of ITPR2 (Q14571)
D232G (p.Asp232Gly) in ITPR2 (Q14571) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
D232G (p.Asp232Gly) variant details
- p.Asp232Gly
- NCI-TCGA Cosmic COSV6726
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.722
- REVEL 0.77
- CADD 27.40
- PolyPhen-2 0.94
- SIFT 0.11
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available