Y76Y (p.Tyr76Tyr) variant of ITK (Tyrosine-protein kinase ITK/TSK)
Y76Y (p.Tyr76Tyr) in ITK (Tyrosine-protein kinase ITK/TSK) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
Y76Y (p.Tyr76Tyr) variant details
- p.Tyr76Tyr
- rs140451238
- gnomAD 5-157208978-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.225
- CADD 6.59
- Most common in the 1KG:ASW population (allele frequency 0.0098)
- Structural context available
- Literature evidence available