V63I (p.Val63Ile) variant of ITK (Tyrosine-protein kinase ITK/TSK)
V63I (p.Val63Ile) in ITK (Tyrosine-protein kinase ITK/TSK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
V63I (p.Val63Ile) variant details
- p.Val63Ile
- gnomAD 5-157208937-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.611
- REVEL 0.64
- ESM-1b 0.00
- AlphaMissense 0.21
- CADD 24.00
- PolyPhen-2 1.00
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available