V63G (p.Val63Gly) variant of ITK (Tyrosine-protein kinase ITK/TSK)
V63G (p.Val63Gly) in ITK (Tyrosine-protein kinase ITK/TSK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data, published literature, and structural context.
V63G (p.Val63Gly) variant details
- p.Val63Gly
- gnomAD 5-157208938-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.843
- REVEL 0.95
- ESM-1b 1.00
- AlphaMissense 0.84
- CADD 27.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available