T34A (p.Thr34Ala) variant of ITK (Tyrosine-protein kinase ITK/TSK)
T34A (p.Thr34Ala) in ITK (Tyrosine-protein kinase ITK/TSK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
T34A (p.Thr34Ala) variant details
- p.Thr34Ala
- gnomAD 5-157181077-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.645
- REVEL 0.64
- ESM-1b 1.00
- AlphaMissense 0.35
- CADD 23.80
- PolyPhen-2 0.09
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available