N86T (p.Asn86Thr) variant of ITK (Tyrosine-protein kinase ITK/TSK)
N86T (p.Asn86Thr) in ITK (Tyrosine-protein kinase ITK/TSK) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
N86T (p.Asn86Thr) variant details
- p.Asn86Thr
- gnomAD 5-157211298-CA-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.509
- CADD 26.50
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available