L88L (p.Leu88Leu) variant of ITK (Tyrosine-protein kinase ITK/TSK)
L88L (p.Leu88Leu) in ITK (Tyrosine-protein kinase ITK/TSK) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
L88L (p.Leu88Leu) variant details
- p.Leu88Leu
- gnomAD 5-157211307-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.172
- CADD 4.46
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available