H84Y (p.His84Tyr) variant of ITK (Tyrosine-protein kinase ITK/TSK)
H84Y (p.His84Tyr) in ITK (Tyrosine-protein kinase ITK/TSK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
H84Y (p.His84Tyr) variant details
- p.His84Tyr
- gnomAD 5-157211293-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.36
- ESM-1b 0.00
- AlphaMissense 0.20
- CADD 14.30
- PolyPhen-2 0.08
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available