F92Y (p.Phe92Tyr) variant of ITK (Tyrosine-protein kinase ITK/TSK)
F92Y (p.Phe92Tyr) in ITK (Tyrosine-protein kinase ITK/TSK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
F92Y (p.Phe92Tyr) variant details
- p.Phe92Tyr
- gnomAD 5-157211318-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.611
- REVEL 0.52
- ESM-1b 1.00
- AlphaMissense 0.64
- CADD 24.00
- PolyPhen-2 1.00
- SIFT 0.33
- Population evidence available
- Structural context available
- Literature evidence available