E64E (p.Glu64Glu) variant of ITK (Tyrosine-protein kinase ITK/TSK)
E64E (p.Glu64Glu) in ITK (Tyrosine-protein kinase ITK/TSK) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
E64E (p.Glu64Glu) variant details
- p.Glu64Glu
- gnomAD 5-157208942-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.466
- CADD 9.27
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- Literature evidence available