A36T (p.Ala36Thr) variant of ITK (Tyrosine-protein kinase ITK/TSK)
A36T (p.Ala36Thr) in ITK (Tyrosine-protein kinase ITK/TSK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A36T (p.Ala36Thr) variant details
- p.Ala36Thr
- ExAC rs778189459
- gnomAD rs778189459
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.15
- ESM-1b 0.00
- AlphaMissense 0.06
- CADD 13.90
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available