A36G (p.Ala36Gly) variant of ITK (Tyrosine-protein kinase ITK/TSK)
A36G (p.Ala36Gly) in ITK (Tyrosine-protein kinase ITK/TSK) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
A36G (p.Ala36Gly) variant details
- p.Ala36Gly
- gnomAD rs1753503783
- Missense
- Variant Prioritization Score for Impact Estimate 0.333
- REVEL 0.26
- ESM-1b 0.00
- AlphaMissense 0.10
- CADD 21.50
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available