W11L (p.Trp11Leu) variant of ITGB3 (Integrin beta-3)
W11L (p.Trp11Leu) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
W11L (p.Trp11Leu) variant details
- p.Trp11Leu
- TOPMed rs941154306
- Missense
- Variant Prioritization Score for Impact Estimate 0.509
- MetaLR 0.11
- MetaSVM -1.06
- CADD 21.90
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 2.1e-06)
- Structural context available