W11C (p.Trp11Cys) variant of ITGB3 (Integrin beta-3)
W11C (p.Trp11Cys) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
W11C (p.Trp11Cys) variant details
- p.Trp11Cys
- gnomAD 17-47253894-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.508
- MetaLR 0.07
- MetaSVM -0.94
- CADD 22.90
- PolyPhen-2 0.09
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available