V25L (p.Val25Leu) variant of ITGB3 (Integrin beta-3)
V25L (p.Val25Leu) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
V25L (p.Val25Leu) variant details
- p.Val25Leu
- gnomAD 17-47253934-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- MetaLR 0.07
- MetaSVM -1.07
- CADD 19.30
- PolyPhen-2 0.00
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available
- Literature evidence available