V25A (p.Val25Ala) variant of ITGB3 (Integrin beta-3)
V25A (p.Val25Ala) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
V25A (p.Val25Ala) variant details
- p.Val25Ala
- gnomAD 17-47253935-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- MetaLR 0.05
- MetaSVM -1.09
- CADD 16.40
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available
- Literature evidence available