R8W (p.Arg8Trp) variant of ITGB3 (Integrin beta-3)
R8W (p.Arg8Trp) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
R8W (p.Arg8Trp) variant details
- p.Arg8Trp
- TOPMed rs952078066
- gnomAD rs952078066
- Missense
- Variant Prioritization Score for Impact Estimate 0.357
- MetaLR 0.03
- MetaSVM -0.99
- CADD 16.80
- PolyPhen-2 0.04
- SIFT 0.22
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available